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The War on Legal Drugs: Follow The Money

The US is the only industrialized country that doesn’t regulate the price of prescription drugs.

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WHO statistical clock

   

Families USA

Open Secrets

Semantics and party politics

OTTAWA - While federal opposition leaders are lining up to condemn new health care user fees in Quebec, British Columbians and Ontarians surely are scratching their heads.  The fact is, people in the latter two provinces have been paying special health charges for a while now, and no one in Ottawa has batted an eyelash.   (Vancouver Sun)

 

Drug makers unhappy with meth law

SALEM - A meth user can't make methamphetamine without pseudoephedrine, the main ingredient in most over-the-counter cold medicines like Sudafed, so first Oregon and now Missouri and Mississippi have made those medicines available only with a prescription.  Companies such as Johnson & Johnson, Pfizer and Merck say it is too hard for customers to buy cold medicine.  (ABC)  

 

Poli-Grip linked to nerve damage

The maker of Poli-Grip is warning users who have been heavily applying the denture adhesive for several years that they should stop using the product immediately.  (CTV)    MORE:  Zinc in denture creams health risk

 

Alzheimer's to escalate

Canada needs a national strategy to prepare for a tidal wave of dementia cases in the coming decades that could swamp the health-care system and put a severe drain on the economy, a new report says.  (Toronto Star)

 REPORT:  Rising tide   Dementia surge to cost $153B by 2038   Alzheimer's disease    Too late for the current generation of politicians

 

Cost of doing business

NEW YORK - Across the US, pharmaceutical companies have been pleading guilty to criminal charges or paying penalties in civil cases when the US Department of Justice finds that they deceptively marketed drugs for unapproved uses, putting millions of people at risk of chest infections, heart attacks, suicidal impulses or death.  Since May 2004, Pfizer, Eli Lilly & Co, Bristol-Myers Squibb and four other drug companies have paid a total of $7B in fines and penalties.  As drugmakers repeatedly plead guilty, they’ve shown they’re willing to pay hundreds of millions of dollars in fines as a cost of generating billions in revenue.    (Bloomberg)  

 

Drug websites shut down

The public are being warned of the dangers of buying unlicensed medicines on the internet. The alert comes as hundreds of websites are being shut down for selling fake or illicit drugs around the world.   Interpol and the UK MHRA co-ordinated raids and public awareness campaigns in 24 countries this week. (Times online)     MORE:   Police warn of counterfeit drugs   RCMP, CBSA join effort   Web drugs overwhelmingly fake   FDA issues warning letters   Internet sting nets drugs

 

Cash up front

OTTAWA - Health Canada is getting tough with patients who use government-certified medical marijuana, demanding full payment in advance before shipping the weed. Previously, users could order and pay later. But hundreds of patients - who are often seriously ill, unable to work and on welfare or disability pensions - could not keep up with their Health Canada bills and built up large debts.  (CTV) 

 

Overdose death sparks class action suit

EDMONTON - Fentanyl is an opiate 80 to 100 times as strong as morphine, and approved for use as a pain medication in Canada and the US.   (Edmonton Journal)

 

Proposals set to rile legal drug industry

TORONTO - A new war is brewing over Canada's multi-billion-dollar prescription-drug business, fuelling death threats against a top government official, plans for a major lobbying campaign and predictions of furious political debate to come.   (National Post)  PREVIOUS:  Taxpayers on the hook   Tax hikes loom

 

Drug industry at the crossroads

WASHINGTON - Facing unprecedented pharmaceutical patent expirations over the coming years and subsequent competition with generic drug makers pharmaceutical companies are searching frantically for new cash cows or different business models to stabilize their businesses. (Epoch Times)  PREVIOUS:  Cardiovascular drug costs triple   Long-term trends in use and expenditures for cardiovascular medications in Canada   

 

Dying in pain

ST. JOHN’S - A scathing report has found that few of the people who die in Newfoundland and Labrador have access to appropriate palliative care, and spend their final days in needless anguish.  (CBC)   REPORT:  Needs assessment of palliative care   .pdf

 

Cut ties

OTTAWA - A federal Conservative MP whose 15-year-old daughter collapsed and died after taking a prescription medication will this week introduce a private member's motion calling for an arm's length drug safety agency.  (CBC)   MORE:  Loophole in unapproved drugs process   Death by Prescription

 

Doctor fixed data

Andrew Wakefield, the doctor who sparked the scare over the safety of the MMR vaccine for children changed and misreported results in his research, creating the appearance of a possible link with autism.   (Times online)    PREVIOUS:  MMR vaccine controversy

Entitled get preferred treatment

Politicians and top bureaucrats from provinces across the country have better access to cancer drugs and treatment than their constituents, according to Cancer Advocacy Coalition Canada. (QMI)   Report card on cancer in Canada .pdf 

 

Slow to get approval

TORONTO - Canadians are not able to quickly access newly developed prescription medicines because of the slow drug approval process and delays by provincial drug plans in approving the medicines for reimbursement, according to a new study released by a leading Canadian think-tank. (CanWest) REPORT:  Access delayed, access denied     7 legal drugs that can kill kids in a single pill    Legal highs

 

Generic drug deal

EDMONTON - Most generic drugs in Alberta will soon cost patients and the province less, after a new provincial agreement with national drug chains and Alberta pharmacists.  (CBC)    MORE:  Alberta pharmacy plan   

 

Meds cause personality changes

Antidepressant medications taken by roughly 7% of American adults cause profound personality changes in many patients with depression, far beyond simply lifting the veil of sadness, a study has found.  (LA Times)   STUDY:  Personality change during treatment   OD's skyrocketing   Pain relievers linked to more deaths  

 

Anti-psychotic drugs

LONDON - Up to 150,000 people with dementia are being prescribed anti-psychotic drugs unnecessarily, a Government-ordered review disclosed.  Only around 36,000 of the 180,000 people on the drugs in the UK derive any benefit from them, it said.  Over prescribing of the drugs is linked to an extra 1,800 deaths a year among elderly people.  (Telegraph UK)

 

Amgen sued

NEW YORK - New York, California and 13 other states are accusing biotech giant Amgen Inc. of offering kickbacks to medical providers to boost sales across the country of its anemia drug Aranesp, which increasingly has been beset by safety concerns.  (LA Times)   MORE:  NY AG statement

 

Superbugs kills 30,000 over 5 years

LONDON - The number of people dying due to MRSA and Clostridium difficile fell sharply last year but the superbug infections were still responsible for 30,000 deaths in five years, figures show.   (Times online)  ONS

 

Scheme to let drugs bypass watchdog

LONDON - Drug companies with "innovative" medicines would be able to bypass current safeguards and sell to the NHS at a high price under a fast-track procedure to be proposed next week by the Office for Life Sciences (OLS), run by science minister Paul Drayson.  (Guardian UK)   PREVIOUS:  How Drayson fattened up his drug firm on the taxpayer   NICE

 

Drug company loophole

VANCOUVER - Drug companies can do in Canada what they can’t in the US: advertise prescription drugs even if they carry risks for life-threatening complications, according to a UBC study. (Vancouver Sun)

 

Pharmaceuticals in our water

US manufacturers, including major drug makers, have legally released at least 271 million pounds of pharmaceuticals into waterways that often provide drinking water - contamination the federal government has consistently overlooked, according to an Associated Press investigation.  (AP)  PREVIOUS:  Factories dumping drugs into sewage

 

Misused and abused

Medical specialists in Canada have released a set of guidelines for physicians to use when prescribing opioid medications to address concerns the drugs are being misused and abused by patients.   (CanWest)  PREVIOUS:  Health plan funds killer drug   OxyContin

 

Selling free samples

The PEI Pharmacy Board is looking for help from the public to find out if some pharmacies on the Island are selling for full price drugs that were provided as samples to doctors.  The doctors get the samples for free from drug companies.  (CBC)   RELATED:   New deal gives ON MDs 12% pay increase

 

Technology could change health care

Advances in health care run the gamut from mind-boggling medicines to simple web solutions that, if adopted, could slice huge slabs of fat from a bloated system.   Whatever form innovation takes in the coming years, much of it will spring from start-ups, not pharma and tech giants.  (Forbes)   

 

Canadians still waiting too long

Canadians are waiting less long for surgery, but are still experiencing delays of more than 17 weeks for treatment, according to new research published by the Fraser Institute.  (Vancouver Province)  MORE:   Waiting your turn   CHC blames wait lists on private clinics  

 

UnitedHealth settles cheating claims

UnitedHealth Group Inc., the biggest US health insurer, said it will spend $400 million to settle allegations it has manipulated payments to doctors and patients for the last 15 years.  (Bloomberg)   MORE:  Insurer will pay over 'rigged' information

   

Feeding frenzy for lobbyists

WASHINGTON - The battle over healthcare entered a new, more frenzied stage Wednesday, as lawmakers and powerful interest groups jockeyed for advantage now that most believe some form of an overhaul will ultimately be signed into law.  The Senate Finance Committee's Tuesday passed a sweeping healthcare bill.  Passage of a major bill by the House also is considered increasingly likely.  But that success has spawned a furious scramble among insurers, labor unions and others to protect their interests in the weeks before the House and Senate begin voting on their final healthcare bills.  Now, any financial gain by one group will likely correspond with losses by the others.  (LA Times)

Health care has been good for us

US health spending

Health spending 2008  .pdf 

Balking at costs

Payoff for Senators typical in health care bill   

'It's a bonanza'

Health insurance premiums

Senate committee report

Membership has its privileges

Consumer protections lost in US health care debate

Gutless politicians can't handle the truth  

Lobbyist’s gets a seat at the healthcare trough    

Health care debate shifts to Main Street

Canadian health system is broken

A reality check on a reality check

Health care in the US

Health care in Canada

Pushing for US health care reform

Big money fuels health care battle

Drug makers 1st offer $80B

   

Provinces urged to push for national drug-buying strategy

OTTAWA - Not all cancer patients are treated equally in this country when it comes to the bills for their drugs, and it's about time the federal government stepped up to ensure universal access and coverage, says a new report from the Canadian Cancer Society.  (CanWest)   Cheapest drugs in Canada

Drug spending rising

Canadians spent $30B on legal drugs in 2008

Cancer drugs cost soars

Lost revenue

We have to overcharge or we can't compete

Ontario's 25% makes 50% provinces look bad

New rules

Ontario's ruinous Medicare habit

Drug spending estimated at $30B in 2008

Drug costs have ballooned in Quebec

Part 1: Cost of Cancer drugs   .pdf

Part 2: Who is bearing the cost?  .pdf

National health expenditures trends 1975-2008  .pdf  

   

WHO denies exaggerating threat

GENEVA - The World Health Organization (WHO) denied that it was unduly influenced by drugs companies to exaggerate the dangers of the H1N1 flu virus.  Pharmaceutical firms picked up multi-million dollar vaccination contracts when the United Nations health agency declared the flu a pandemic last June.  (Reuters)  

Canada donates 5M doses of vaccine to WHO

Ottawa ponders H1N1 vaccine surplus

EU to investigate WHO and 'pandemic'

France sells off surplus vaccine

How vaccines became big business

The ties that bind even apparent in Cancer Research

Health bosses accused of flu-mongering

Manufacturing one crisis after another

What to do now

FDA wants warning on flu drugs

GSK contract awarded in 2001 by Liberals

WHO review  

Flu shots futile

H1N1 risks exaggerated  

H1N1 overplayed by media, public health

How to screw up

'Flu rage'

'Gaming the system'

Provinces try to reduce vaccine lineups

Death toll predictions slashed

20,000 seasonal flu deaths in UK 

MD group defends $500 per hour

Flu fear may be good for us

No flu pay for AB nurses

'A whole industry is waiting for a pandemic'

Feds blasted over single supplier

Notes on a non crisis

Hockey players should wait

Vaccine surplus sent abroad

800 seasonal flu deaths a week reported in US

Vaccine phobia runs deep

H1N1 a national emergency

48% Canadians not keen on vaccine

Swine flu death rate similar to seasonal

In line for swine flu vaccine

Health officials slam CMAJ for H1N1 report

Canada to buy 50.4M doses of vaccine

Canadian Premiers sound alarm on flu threat

Big drop in new swine flu cases

Half of health staff would refuse flu shot

How safe is the swine flu vaccine?

WHO says flu vaccines will be safe

Pandemic alert must show 'actual' danger  

Drug rebates questions on cost, transparency

Vaccine will need compensation rules

Swine flu ‘unstoppable'

2009 swine flu outbreak

$1B awarded for flu vaccine

France to spend 1B euros

US to spend another $1B for flu vaccine

WHO: Swine flu vaccine access biased to rich

Canadian court upholds cash cow rules

Rush for gold

Global deaths top 700

WHO to stop counting flu cases

600% markup on flu vaccine

2009 swine flu outbreak

Rush for gold

WHO:  vaccines for H1N1

Pandemic exposes system flaws on reserves

Pandemic

Oink is proving to be far worse than bite

More harm than good

WHO contradicts UK Tamiflu policy

WHO predicts 'explosion' of swine flu cases

Appoint swine flu health czar: CMAJ 

Swine flu vaccine linked to killer nerve disease

Diarrhea, TB more deadly than swine flu

Side-effects outweigh benefits

Officials urge WHO to change alert

Confirmed swine flu cases including 80 deaths

Experts investigate if swine flu evolved in lab

Swine flu may be human error

Adrian Gibbs  

Mexico to begin lifting flu curbs

20 countries ban pork

UK buys 90M doses of vaccine

Roche holding     Tamiflu

WHO's credibility

Mexico sends plane to retrieve Mexicans

Canadians 'having a nice quarantine'

Death toll drops

Potential pandemic or garden-variety flu?

Flu, fear, wasted millions

Cashing in on fear

China quarantines tourists

Living in a culture of fear

WHO dismisses claims it is 'hyping' flu threat

Report on China origin of swine flu 'groundless'

Seasonal flu kills an average of 4,000 Canadians

Man infects pigs with swine flu

   

Canadian named as ghostwriter

TORONTO - A top Canadian researcher studying hormone replacement therapy was part of a ghostwriting scheme paid for by drug giant Wyeth Pharmaceuticals to promote its products.    (Toronto Star) 

Ghostwriting is bad medicine  

Drug ‘reports’ found to be faked  

Why doctors can't rely on medical literature

Doctors signed Merck's Vioxx studies

Another shoe drops in faked studies

Court told of plot to destroy drug critics

Merck wins reversal of Vioxx ruling in Saskatchewan

Merck to pay $4.85B

Merck & Co.

Merck ruling 'huge' impact for Canada

Merck abandons HIV trials

Brazil issues compulsory 'licence'

Journal challenges Canadian led Vioxx study

Merck denies holding back damning Vioxx info

Merck & co. vows to appeal $253M judgment

With Vioxx gone, now what do I do?

Report: Vioxx linked to thousands of deaths

Arthritis drug Vioxx recalled

10 on FDA Vioxx panel had ties to companies

Center for Science in the Public Interest

Merck recalls kids' vaccine

   

US bans key Indian drug imports

WASHINGTON - The United States Food and Drug Administration (FDA) says it has banned the import of more than 30 generic drugs made by Indian drug firm Ranbaxy.   (BBC)   PREVIOUS:   Ranbaxy Canada   FDA defends plastic linked with health risks   Common plastics chemical linked to human diseases   Medical experts fight drug industry influence

You have mental health issues

Dr. Allen Frances had calculated that the recommendations contained within the first draft for the fifth and latest revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM5) could unnecessarily trigger wholesale "epidemics" of mental illness.  (CanWest)  PREVIOUS:  Psychiatry manual's secrecy criticized   DSM

   

Cheap air travel 'is spreading deadly diseases'

UN - People are at greater risk of contracting potentially lethal infectious diseases because of the boom in international air travel, the World Health Organisation (WHO) has warned.    (Telegraph UK)  MORE:  WHO predicts more global epidemics 

EU broadens inquiry

BRUSSELS - European antitrust investigators are expanding the scope of a major inquiry into the $942B pharmaceutical market in a bid to determine whether companies are blocking generics makers from getting less-expensive medicines to market quickly.  MORE:  Pharmaceuticals sector inquiry

   

Big waste of money

NEW YORK - Direct-to-consumer (DTC) advertising has only a modest effect on the sale of drugs, according to research released online by BMJ, a British medical journal.    (Washington Post)   RELATED:  Outsourcing the Drug Industry

Chantix use banned

WASHINGTON - The chorus of consumer complaints about the drug, Chantix (Champix in Canada) is getting louder and louder.   (Injury Board)  PREVIOUS:   Safety signal seen for Varenicline risks   Champix wins Health Canada approval

   

Drug side effects lead to ER

VANCOUVER – 12% of patients who rush to the emergency room at Vancouver General Hospital are there because of adverse effects from medications, according to study findings being published Tuesday in the Canadian Medical Association Journal.  (Vancouver Sun)   PREVIOUS:  Drug errors hurt 1 in 15  More profit than progress in research  Your kid's drug source

Conflict of interest

ATLANTA - A prominent Emory University psychiatrist received at least $2.8 million in consulting fees from companies whose drugs he was evaluating and failed to report a third of it, congressional investigators studying medical conflicts of interest said.   (Los Angeles Times)   MORE:  Psychiatrist failed to report $1.2M   Charles B. Nemeroff

   

Glass 'half full'

OTTAWA - Canada's progress in renewing health-care delivery halfway into the 10-year term of a historic accord is spotty, a new report says.  (CTV)   REPORT:  Health care renewal in Canada 2003-2008   Canadian drug spending estimated at $27B in 2007

Drug suit can target profits

TORONTO - A class action by nearly 600,000 Canadians suing the makers of the popular antipsychotic drug Zyprexa has been given the go-ahead by the Ontario Superior Court of Justice to target the company's profits.  (Toronto Star)

   

Drug maker turned to Giuliani

NEW YORK - In western Virginia, far from the limelight, US Attorney John L. Brownlee found himself on the telephone last year with a political and legal superstar, Rudolph W. Giuliani.  For years, Mr. Brownlee and his small team had been building a case that the maker of the painkiller OxyContin had misled the public when it claimed the drug was less prone to abuse than competing narcotics.   (NY Times)

Strep outbreak kills 10

THUNDER BAY - The local health unit warned today of a possible streptococcal disease outbreak in the city that has already killed 10 people. The Thunder Bay District Health Unit is investigating an outbreak of invasive Group A streptococcal infection.   Since August 2007, there have been 75 cases in Thunder Bay and District.  (Thunder Bay Source)   MORE:  Strep outbreak kept secret   Strep outbreak likely to spread

   

Widespread off-label drug prescription

Thousands of times a day in Canada, patients are prescribed drugs “off-label,” meaning for conditions for which they have never been approved.   (CanWest) 

Fentanyl pain patches recalled

OTTAWA - In the latest of several alerts on the safety of fentanyl pain-relief patches, Health Canada has announced the recall of two brands of the powerful patches.  (CTV)

   

Health care lags far behind Europe

TORONTO - Universal health care is something many Canadians cherish and want to fiercely protect, but a new study finds it lags far behind the standard of care that is commonplace in Western Europe.  (CP) 

Euro-Canada Health Consumer Index 2008

A $13B question for health czars

MB below average

ON's tops

QC's system fares poorly

Poor grade for SK's health care

   

Harmful drugs in St Lawrence River

Montreal's waste-water treatment plant in Rivière des Prairies is treating an average of 32 square metres of waste water a second before releasing it into the St. Lawrence River.  (Montreal Gazette)  

Meds in treated Montreal wastewater

World's highest drug levels

Traces of drugs in tap water

More testing sought

Drugs in drinking water

   

Few doctors use electronic records because of costs

BOSTON - Electronic health records (EHR), touted by the government as a way to reduce medical costs, are used by few doctors in the US because they are too expensive for their practices, a Harvard University survey found.  The poll, published in the New England Journal of Medicine, found that just 4% of doctors use software that includes electronic prescriptions and drug-interaction warnings.  (Bloomberg)     EHR priority for Canada

The need for an Institute

Currently, continuing medical education activities are, for the most part, sponsored by the pharmaceutical industry, which has a vested interest in promoting its products. This is big business: of the $2.6B spent in the US on accredited continuing medical education activities in 2006, $1.45B (60%) came from pharmaceutical and medical device manufacturers. (CMA Journal)  PREVIOUS:   CMA Journal takes on drug firms   Global Pharmaceutical market $643B in 2006  

   

Report faults FDA on trial audits

WASHINGTON - The Food and Drug Administration does very little to ensure the safety of the millions of people who participate in clinical trials, a federal investigator has found.  In a report released Daniel R. Levinson, said federal health officials do not know how many clinical trials are being conducted, audit less than 1% of the nation's testing sites, and, on the rare occasions when inspectors do appear, generally show up long after the tests are completed.  (NY Times)

Lax oversight

FDA’s oversight of investigators’ financial information    .pdf

FDA may miss researchers' financial conflicts

Knowledge gap

Report slams FDA's drug approval system

The future of drug safety

   

Seniors high-risk medications

More than one in four Canadian seniors are still taking medications that are potentially harmful for their age group, finds a study released today by the Canadian Institute for Health Information.   (CTV)  STUDY: Drug claims by seniors: 2000-2006   More bad news for diabetes drug

Work related stress can kill

LONDON - Work really can kill you, according to a study on Wednesday providing the strongest evidence yet of how on-the-job stress raises the risk of heart disease by disrupting the body's internal systems.   (Reuters)   PREVIOUS:   Whitehall II    Miscarriage risk with 2 coffees a day

Deadly parasite taint child medicines

OTTAWA - Health Canada is advising consumers not to use two foreign natural health products to treat digestive upset in infants and children because of potentially dangerous contamination.   (Toronto Star)   MORE:  Health Canada issues warning

Power to probe hospitals urged

TORONTO - Ontario is the only Canadian province where hospitals aren't subject to the scrutiny of an ombudsman - an "extremely alarming" oversight that compromises public safety, according to Ontario Ombudsman André Marin.   (Toronto Star)

   

Judge throws out price-fixing case

LONDON - The criminal prosecution against Goldshield and four other drug companies over allegations they conspired to overcharge the NHS for generic medicines was part of the largest case ever launched by the agency. Judge Pitchford made an order banning the reporting of his reasons for rejecting the SFO's case.   (Times online)

Drug giants accused over doctors' perks

SFO humiliation

NHS pays too much for its drugs

5 companies charged in NHS price fixing row

Drug firm accused

Reckitt Benckiser

Britain 'hooked on painkillers'

'Suicide rating' could be given to new drugs

   

A cancer vaccine with political will or powerful lobbying 

It has been called "the medical breakthrough of the 21st century" and the most significant development in women's reproductive health since the Pill. (National Post)  PREVIOUS:  Gardasil   Merck & Co.   Cervarix    GlaxoSmithKline

'Bio-Identical' hormone claims unsupported

WASHINGTON - US health officials warned seven pharmacy operators on Wednesday that their claims about the safety and effectiveness of "'bio-identical" hormones were false, misleading and not supported by medical evidence.   (Reuters)

   

Doctors rely too heavily on drug company data: CMA

Most of the information doctors receive about prescription drugs comes from the very companies making the product, a doctor said Wednesday, pointing to a possible reason why doctors continue to prescribe dangerous drugs to seniors.  (CBC)  PREVIOUS:   Drugs continue to be prescribed   Off Limits

No Contradiction

MONTREAL - Less than two months after quitting politics, Quebec's former health minister Philippe Couillard accepted a lucrative private-sector job that trumpets the future of private health care.   Couillard was recruited as a partner at Persistence Capital Partners, Canada's first private equity fund that invests in health care businesses.  (Montreal Gazette)

   

Doctors exploit addicts

Ontario needs to crack down on doctors who have turned drug addiction therapy into a money-making venture, a provincial report says.    (Toronto Star)

Blunders 'kill 90,000 patients'

LONDON - More than 90,000 patients die and almost one million are harmed each year because of hospital blunders, research suggests.   (Telegraph UK)

   

MD faked billings

TORONTO - A Toronto family doctor admitted yesterday to pumping more than 130,000 prescription sedatives into the black market and defrauding Ontario's health care system of more than $750,000.  (Toronto Star)

12 MDs top $1M in billings

WINNIPEG - Twelve Manitoba doctors topped the medical millionaire mark in billings to the province last year, including one pathologist who claimed $9.2 million in fees.    (Winnipeg Free Press) 

   

Painkiller use rising

MYRTLE BEACH, SC - People in the US are living in a world of pain and they are popping pills at an alarming rate to cope with it.  The amount of five major painkillers sold at retail establishments rose 90 percent between 1997 and 2005, according to an Associated Press analysis of statistics from the DEA.  (AP)  

Threat of world pandemic over

A quarter of a century after the outbreak of AIDS, the World Health Organization (WHO) has accepted that the threat of a global heterosexual pandemic has disappeared. (Independent UK)  REPORT:  World health statistics 2008   WHO's department of HIV/Aids   HIV patients live years after diagnosis

   

Another West Nile death

REGINA - The West Nile virus has killed an elderly woman in the Regina Qu'Appelle Health Region and, as health officials predicted last week, the number of cases this year has reached a record high.  (Regina Leader-Post)  PREVIOUS:  Canada invests $199M in flu vaccine   GlaxoSmithKline

Anguish of pharmacoeconomics

A year after Ontario introduced new legislation that promised to make drug approvals more transparent, key parts of that legislation have still not been implemented.  (Ottawa Citizen)   PREVIOUS:  Statistics Canada: Deaths by selected grouped causes    List of causes of death by rate

   

Unauthorized drug being sold

OTTAWA - Health Canada is trying to halt the sale and use of Resolve, a product used to help quit smoking, because of a potential health risk to consumers.  (CanWest)   MORE:   Smoking cessation product is risky

Avandia raises heart-death risk

CHICAGO - Avandia, GlaxoSmithKline Plc's widely used drug for treating type 2 diabetes, increased the risk of heart death by 64% and the risk of heart attack by 43%, US researchers said.  (Reuters)  GSK knew of risks   Glaxo settles Paxil lawsuit  

   

Free trade zones ease passage

DUBAI, UAE - Three months ago, when the authorities announced that they had seized a large cache of counterfeit drugs from Euro Gulf's warehouse deep inside a sprawling free trade zone here, they gave no hint of the raid's global significance. 

Warning over fake medicines

Chinese gangs 'behind fake drugs'

Fighting fake drugs

The new scramble for Africa

U of Toronto G8 information guide

Warning of 'fake sites' pushing pills

   

Class action

MONTREAL - Relatives of patients who either were infected or died from C. difficile diarrhea during an outbreak at a St. Hyacinthe hospital in 2006 have launched a class action against the local health authority for up to $10 million in damages.  (Montreal Gazette)  

C. difficile

Victims sue hospital

Hospital sued for $50M

Lethal germ hits hospital

Hospital director 'kept in the dark'

13th death from C. difficile at Montreal hospital

   

Physicians signal frustration, elect private-care chief

CHARLOTTETOWN - Canadian doctors signalled their frustration with Canada's health care system yesterday, overwhelmingly approving a call to allow physicians to practise both private and public medicine, and choosing the co-owner of a private clinic as their new president.  (CanWest)   PREVIOUS:  When doctors do politics    Canadian Government Directive on Regulating   National Professional Organizations  

Cancer top killer

OTTAWA - The number of Canadian deaths caused by cancer may soon overtake those caused by cardiovascular disease, according to a new study.  Statistics Canada reported Friday that over the past 25 years, the number of deaths caused by cardiovascular diseases has been declining while cancer-caused deaths have been on the rise.  (CTV)   REPORT:  Mortality, summary list of causes 2004    Tables   Cancer from X-rays kills hundreds a year

   

Medical journal criticizes WHO for neglecting evidence

When developing "evidence-based" guidelines, the World Health Organization routinely forgets one key ingredient: evidence. That is the verdict from a study published in The Lancet online Tuesday.  The medical journal's criticism of WHO could shock many in the global health community, as one of WHO's main jobs is to produce guidelines on everything from fighting the spread of bird flu and malaria control to enacting anti-tobacco legislation.  (AP)   MORE:  WHO guidelines report  .pdf

Unapproved drugs given to kids

Antipsychotics are being widely prescribed to children with behaviour and mood problems, with a significant proportion going to children under nine, new research shows.  Ninety-four per cent of 176 child psychiatrists in Canada surveyed are prescribing powerful drugs known as atypical antipsychotics for a variety of disorders and symptoms, including anxiety, attention-deficit hyperactivity disorder and "poor frustration tolerance."  (CanWest)   MORE:  Child's death raises concerns about psychiatric drugs   Nursing homes give seniors antipsychotic drugs they don't need

   

Most doctors accept freebies

WASHINGTON - Four out of five doctors surveyed in the United States said they let drug and device makers buy them food and drinks despite recent efforts to tighten ethics rules and avoid conflicts of interest.   (AP)   PREVIOUS:    National survey of physician-industry relationships   Characteristics and Impact of Drug Detailing   The drug pushers   Big business behind your doctor's diagnosis

Free drug samples go to wealthy

WASHINGTON - The pharmaceutical industry contends that the samples help the uninsured and people with low incomes, but the study of prescription use by nearly 33,000 US residents during 2003 found that the neediest were least likely to get samples.  (Reuters)    PREVIOUS:  Characteristics of recipients of free prescription drug samples     The Cost of pushing pills

   

US drug company to move trials to Canada

MONTREAL - SFBC International, a controversial drug development company under Senate investigation in the United States says it will close its beleaguered Florida labs and transfer planned clinical trials to Canada.  (CTV)   PREVIOUS:  Big Pharma's shameful secret 

AIDS drugs fiasco a tale of red tape

As Canadian officials bickered about why Canada's Access to Medicines Regime failed to send one generic AIDS pill to needy countries, thousands of people died of the disease in Rwanda.  (Toronto Star)   PREVIOUS:   US super market to offer free antibiotics   Rwanda launches key test

   

Jury find Wyeth liable

RENO, Nev. - A jury levied a $134.5M judgment against pharmaceutical giant Wyeth in a lawsuit filed by three Nevada women who claimed the company's hormone replacement drugs caused their breast cancer.  (AP)   Warning issued over drug   Venlafaxine   Wyeth   Popular painkillers can raise heart risk

FBI raids office of Bristol-Myers CEO

NEW YORK - Agents for the Federal Bureau of Investigation raided the office of Bristol-Myers Squibb Co. Chief Executive Peter Dolan as part of a criminal antitrust probe, The Wall Street Journal reported.  (Reuters)   Drugmaker to pay SEC $150M

 

   

No 'rational discussion' at AIDS conference

ANTIGONISH, NS - The federal minister of health says he didn't make funding or policy announcements at the International AIDS Conference because overwrought delegates were making it impossible to have a "rational discussion."    (CP)

Leave PM out of AIDS fight

Harper: AIDS conference too 'politicized'

AIDS cases drop, but due to revised data

IAVI: More than $20 billion spent globally each year on AIDS research, treatment, prevention and care

Suit over Aids drug price hike

US refuses to lower AIDS drug cost

UN AIDS site

AIDS out of control in India

Government tested AIDS drugs on foster kids

   

Stuck on meds

In the almost two decades since Prozac  - the first of the antidepressants known as SRIs, or serotonin reuptake inhibitors — hit the market, many patients have reported extreme reactions to discontinuing the drugs. (AP)  

Spending to death: How much is living worth?

Dying of lung cancer, Carolyn Hobbs tried a new biotechnology drug that produced an unanticipated side effect: acute sticker shock.   (AP)  

   

Study: Teens use medicines to get high

WASHINGTON - Teens increasingly are getting high with legal drugs like painkillers and mood stimulants, and they're turning to cough syrup as well, says a government survey.  (AP) 

NIDA: Decrease in illicit drug use

Teen prescription drug abuse 'entrenched'

Partnership attitude study (PATS) 2005

Teen develops way to detect disease in body

Caffeine linked to psychiatric disorders

Study suggests youth abuse caffeine

   

10M children die

MANILA - Use of existing, low-cost tools and knowledge could save more than 6 million of the 9.7 million children who die yearly from easily preventable or curable causes, the report said.  They include antibiotics that cost less than $0.30 to treat pneumonia and oral rehydration therapy (cost about $0.10) for diarrhea.  (AP)

Annual Report 2007   .pdf 

State of the World's Mothers 2008  .pdf

18,000 kids dies each day from hunger: UN

World Food Program

UN: Lack of sanitation kills millions every year

UN Development Program Report 2006

29,000 kids die each day

Global child survival and health

   

Antidepressants linked to suicide

TORONTO - Elderly people who take a popular type of antidepressants are almost five times more likely to commit suicide than those on other antidepressants, concludes a major new Canadian study that adds to the controversy around the drugs known as SSRIs.  (CanWest)  

 

Institute for Clinical Evaluative Sciences (ICES)

Ephedra supplier now facing bankruptcy

Supplements maker denies evidence of side effects

   

FDA scientists mistrusts FDA

WASHINGTON - About two-thirds of Food and Drug Administration scientists are less than fully confident in the agency's monitoring of the safety of prescription drugs now being sold, according to an FDA internal survey.   (CBS)

Claritin maker coughs up $346M

A Review of 2004's drug controversies

FDA 'incapable of protecting America'

Questions raised about arthritis drugs

Health, United States 2004

Accidental addicts

   

Petitions to FDA delay generic drugs

When its hot-selling antidepressant Wellbutrin XL was facing the prospect of competition from cheaper generics late last year, Biovail Corp. filed a "citizen petition" with the Food and Drug Administration, raising concerns about the safety of its potential rivals. (Washington Post)    RELATED:  The lawlessness of the FDA

Drug firms' research spending falls short

OTTAWA - Brand-name drug makers spent $1.2B or 8.7% of their sales on research and development, marking the fifth consecutive year that the industry has failed to meet the 10-per-cent-of-sales ratio pledged when patent rules were strengthened in 1987.  At the same time, the industry's revenues continue to climb.  (Citizen)

   

Spending outpacing provincial revenue

Over the last 10 years, provincial government health-care spending has grown at an average rate of 7.4% while provincial revenue increased by an average of 6.5%.   (CanWest)   

Paying more, getting less  

Health care spending to hit $183B

National health expenditure trends

1st you raise prices

Canadian Institute for Health Information

Canada's health care tab grows to $172B

Watchdog may be scrapped

Thereapeutics Initiative

Drug firm loses round

Illegal drug rebate scheme

Province lays charges in generic-drug payment scheme

Key players in scheme to boost generic drug profits

Canadians still paying too much

Drug prices in Canada & the US 2008

Canadians still getting gouged

Canada's drug price paradox 2008

Drug firms' sway over PharmaCare Task Force

Recommendations of Task Force

Generic drug prices inflated

BC Pharmaceutical task force

Rebates pay for services

BC Pharmacy Association

Generic Drug sector study

Canada's drug price paradox

Ad ban likely saved Canadians $150M in 2006

PMPRB's 2006 annual report

CGPA   Agency eyeing drug prices

Health-care spending $160B

Health care spending to reach $148B

Hospital responses to babies' deaths

On the front line of care

Health-care spending on the rise

Drug firms get 8-year buffer against generics

Young people in Canada: health and well-being

Use of cannabis and other illicit drugs

Family violence in Canada: A statistical profile

Traffic deaths way up in Vancouver

Motor Vehicle Accidental Deaths

Rebates keep generic drugs pricey

Generic showstopper

Drug companies win appeal against watchdog

Comparison of prescription drug plans

Access to drugs is a 'postal cored lottery'

Health authority reviews 15,000 reports

Health Canada uses disputed research

Medical researchers caught faking it

Canadians not winners in generic drug wars

Graduated drug licensing proposed

Patients are 'revenue sources' 

Castonquay task force

Alcohol and illicit drug dependence

Road fatalities

Heart disease, cancer the top killers: Stats Can

Generic drug firms to fight new rules

Questions loom over 'similar' deaths

Provincial expected to spend $96B on health

Health spending continues to rise

Smitherman tells drug companies to tone down rhetoric

Family income and the well-being of children

Canada spends more on drugs, finds survey

Drug spending in OECD countries since 1998

Canada has four-tier health care

SC strikes down Que medicare law

CIHI: Drug spending 2004

Province $5.5 M to enforce smoke-free plan

Government spends more to combat obesity

Generic drug prices inflated

Generic drugs

Quebec won't shelve health report

Norovirus spreading in Winnipeg

Medicines sending thousands to hospital

Court rules Ontario can't be sued

CIHI: Drug Expenditure in Canada 1985 - 2005

Distorted claims feared if remedy ads allowed

Canadian Institute for Health Information

Joint Centre for Bioethics

Ruling rattles Canada Health Care

Prescription drug spending in Canada $19.6B

Drug spending in Canada still on the rise, public sector's share increasing

CIHI: Health Spending 2004

Why Non-Patented Prescription Drugs cost more in Canada than in the US and Europe

   

Canadian drugmaker labelled a bio-pirate in study

UN - The Canadian maker of a supposed natural treatment for impotence is branded a suspected "bio-pirate" by U.S. and South African environmental groups in a new study.  (CanWest)   STUDY:  Out of Africa: Mysteries of Access and Benefit Sharing   .pdf  

Africa Malaria day- action or bombast?

Every year, over 400 million African mothers, fathers and children are stricken by acute malaria.  Every year, Africa Malaria Day (April 25) is marked by promises to bring malaria under control.    (Canadian Free Press)    MORE:  Africa fighting Malaria  

 

Private health firm built on tax dollars

TORONTO - As politicians here debate the private sector's role in health care, InterHealth Canada, a Canadian company with ties to provincial governments, public hospitals and universities is opening and operating new private medical facilities in Britain and the Persian Gulf.   (National Post)

 

Health fraud's new frontiers: Part 1

Health fraud's new frontiers: Part 2

Part 3 is subscription

Health fraud's new frontiers: Part 4

 

Ontario health care: 5 part series

ONTARIO - Lengthy wait times, pervasive doctor shortages and medical errors are among the major health problems ailing Ontario’s system. Health care management in Ontario is perhaps 10 to 20 years behind the rest of Canada. At least one expert says the lag is costing money and lives.  (Osprey Media Special Report)

Rejection rates trigger state investigation

SACRAMENTO - California AG Jerry Brown is joining state regulators in scrutinizing how HMOs review and pay insurance claims submitted by doctors, hospitals and other medical providers.   (LA Times)  MORE:  Lobbyists target returning Congress   Hospitals price gouging uninsured    $1,133 hospital bill to clip toenail prompts suit

 

Pfizer completes settlement

NEW YORK - Pfizer Inc said it completed its $2.3B legal settlement with the government over marketing of its recalled Bextra painkiller and three other medicines, the largest in the US for claims of off-label drug promotion.  (Bloomberg) 

Pfizer lobbying money

Pfizer drafting customers to lobby

Pfizer Inc.

Pfizer's stop smoking drug wins Health Can

Drug giant backs anti-smoking guide

Pfizer quarterly profit tripled

AIDS group sues Pfizer over Viagra ads

Pfizer faulted over drug trials in Nigeria

Pfizer withdraws Bextra from market

Illegal drug marketing admitted

Pfizer: Celebrex poses heart risk

Nigeria buys baby poison antidote

My Pikin tragedy  

Nigeria takes on Pfizer

Violence, 'Godfathers' and corruption in Nigeria

 

20% of human genes have been patented in US

A new study shows that 20% of human genes have been patented in the US, primarily by private firms and universities.  (National Geographic)

Most OTC cough syrups don't work

Most over-the-counter cough syrups don't work, according to guidelines released from the American College of Chest Physicians.  (Forbes)  

 

Prescription drug use higher

The study reported about 6% of the 3,000 junior high and high school students surveyed said they used prescription drugs such as OxyContin, Percocet and Tylenol 3.   (CBC)   Teens say no to drugs   Teens turning to prescription painkillers

2007 student drug use and health survey

Generation Rx

NEW YORK - The nation’s teenagers are increasingly trying prescription drugs such as Vicodin and OxyContin to get high, with the pill-popping members of “Generation Rx” often raiding their parents’ medicine cabinets, according to the latest national study by the Partnership for a Drug-Free America. (AP)  The land of the medicated

 

NIH to ban consulting deals

In response to growing criticism, the National Institutes for Health is set to ban its research scientists from accepting consulting deals and any other form of income from drug companies.  (CBS)

 

Report: Researchers mum on financial interests 

NIH defends consulting deals 

Moonlighting Federal watchdogs

 

Traces of prescription drugs found in tap water

A study of water samples taken from locations near 20 drinking water treatment plants in southern Ontario found evidence of nine different drugs.  (CTV)   RELATED:  Lead levels in water misrepresented across US

Drug Benefit accused of fraud

ALBANY, NY - New York authorities sued one of the nation's largest pharmacy benefit managers on Wednesday accusing Express Scripts Inc. of pocketing as much as $100 million in drug rebates that should have gone to the state.   (CBS News)

 

195,000 US deaths blamed on hospital error

HeathGrades Inc. said its data covers all 50 states and is more up-to-date than a 1999 study from the Institute of Medicine that said 98,000 people a year die from medical errors. (MSNBC) 

OxyContin makers fined

ABINGDON, Virginia - Purdue Pharma L.P., the maker of OxyContin, and three of its executives were ordered Friday to pay a $634.5 million fine for misleading the public about the painkiller's risk of addiction.  (AP)   PREVIOUS: OxyContin execs misled public   DEA: Oxycontin   Purdue Phamaceuticals

 

  FDA may call for stronger antidepressant warning

WASHINGTON - All drugs used to treat depressed children should carry a “black box” warning of the antidepressants’ link to increased suicidal thoughts and actions, says a panel of federal advisers.  (AP)  

Clinical drug trials 'distorted'

FDA mum on suicidal side effects

Youths risk death in drug abuse trend

 

Medical bills make up half of bankruptcies

Costly illnesses trigger about half of all personal bankruptcies, and most of those who go bankrupt because of medical problems have health insurance, according to findings from a Harvard University study.  (MSNBC)

Drug researchers leak secrets to Wall Street

Prices for drugs rise at triple the inflation rate

Medicare Rx cost estimate zooms

Drugstores sue makers over prices

Drug costs soar before 'discount'

AARP Watchdog Report: Drug prices

Prescriptions and profit

Drug prices outpacing inflation

Medicare discount cards from Hell

Bush to sign landmark Medicare legislation

Major provisions of Medicare Bill

 

Drug Industry employs 675 Washington Lobbyists

WASHINGTON DC - Public Citizen found that the drug industry hired 675 different lobbyists from 138 firms in 2002 – nearly seven lobbyists for each U.S. senator, according to federal lobbying disclosure records.  The industry spent a record $91.4 million on lobbying activities in 2002, an 11.6 percent increase from 2001.    Full Public Citizen Report .pdf    Public Citizen

Note: Mitch Daniels, Bush’s director of the office of management and budget, is a former executive at the pharmaceutical giant Eli Lilly.   Whether or not prescription drug coverage can added to Medicare depends on whether there’s money in the federal budget to pay for it. And the man in charge of budgeting the money for the benefit - and determining if there’s a need for price controls is Mitch Daniels.

 

Money paid by the Pharmaceuticals/Health Products industry 2004

Pharmaceutical companies have enjoyed unprecedented increases in profits over the last ten years, with drugs like Viagra and Prozac becoming household names. And, as profits went up, so did the industry’s campaign contributions. The pharmaceutical and health products companies industry, which includes not only drug manufacturers, but also dealers of medical products, and nutritional and dietary supplements, is consistently one of the top 20 industries for campaign contributions. The industry now gives eight times what it did in 1990.   (Center for Responsive Politics)

MORE:   Election 2004 Top industries

 

There is also the matter of rebates and supplemental rebates drug companies pay to state public aid departments for permission to sell drugs to Medicaid beneficiaries.  Which creates a condition of state governments wanting the money on one hand while trying to keep its citizens happen by fighting for lower prices on the other.  This is not unlike the Pension funds which invest funds in the Pharmaceutical companies because of their high profitability while at the same time being pressured by the Pension members who need a higher return on their pension because they have to pay so much for drugs.   Nice cause and effect loops.

All of this of course doesn't take into account any of the politics that are going on between the two US parties.

 

One of the current arguments is that price regulation would stop or slow the development of new drugs.  This appears to be a spin-doctor’s wish as the extensive tax credits to offset research and development costs are too important to the bottom line.   The US government also spends about $23 billion a year on biomedical research though the National Institutes of Health, most of which passes through the NIH to contractors, universities and research institutions.  National Institutes of Health 

 

Drug Companies spend almost 2 1/2 more on marketing and administration as on R&D

WASHINGTON - U.S. drug companies that market the 50 most often prescribed drugs to seniors spent almost two-and-one-half times as much on marketing, advertising, and administration as they spent on research and development. 

Families USA Report 2002  .pdf

Research spending 2nd to marketing

TV ads influence drug prescriptions: US study

1949- The drug story

Company  - Percent of Revenues Spent on Marketing/ Advertising/ Administration

Abbott Laboratories   23%

Allergan   42%

Bristol-Myers Squibb   27%

Eli Lilly and Co.   30%

Merck   13%

Pfizer   35%

Schering-Plough   36%

Wyeth   37%

According to Public Citizen, an advocacy group, the industry's advertising costs rose from $791 million in 1996 to $2.5 billion in 2001.

 

Canadian Council of Better Business Bureaus Consumer:

Information on buying prescription drugs from Canada

Follow the Money. The Pharmaceutical Industry: The Other Drug Cartel   .pdf

Washington State Canadian Pharmacies drug site

 

CBC Indepth: Cross-border Rx

CBC Indepth: Faint Warning

America's Other Drug Problem: A Briefing Book on the Rx Drug Debate .pdf

 
 

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